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Treatment of Urinary Tract Infections in Non-pregnant Women

Most cases cause by ascending infections from urethra to bladder into the bladder. Female urethra is short and colonized by normal bacteria of the vagina.

Occasional infection may arise from hematogenous spread or lymphatic

Most common organisms 80-90% E.coli (O, K, H antigen serotypes)

Risk factors:

Symptoms frequency and urgency, some suprapubic pain

Acute pyelonephritis combination associated fever and chills

Laboratory traditionally- 100,000 single isolte bacteria was used to define UTI. By diagnosing bacteria with colony count 1,000-10,000 in symptomatic patients improve the sensitivity without significant compromising specificity.


Increase resistance to amoxicillin and trimethoprim-sulfamethoxazole as high as 30% in some populations.


Dr. Khalil

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